Lipid Markets Predict Cardiovascular Before Many Years

Dyslipidemia means the abnormal levels of cholesterol and other lipids in the blood. It is a major risk factor for Cardiovascular conditions. High levels of low-density lipoprotein cholesterol (LDL-C) have links to an increased risk of disease. International guidelinesTrusted Source commonly include LDL-C levels as a risk marker for Cardiovascular illnesses.

Risk markers that can assess Cardiovascular risk include high-density lipoprotein cholesterol (HDL-C), which protects against disease risk; and apoB, which transports LDL-C and other lipids linked to Cardiovascular disease to tissues in the body. ApoA-1 transports HDL-C. Research has shown that the ratios of both apoB and apoA-1 have links to an increased risk of heart attackTrusted Source and strokeTrusted Source.

Research led by the Karolinska Institutet in Stockholm, Sweden, examined the link between apoB/apoA-1 ratios and incidence of nonfatal heart attacks, strokes, and Cardiovascular mortality. The results appear in PLOS Medicine.Prof. Göran Walldius, senior author and professor emeritus at the Institute of Environmental Medicine, Unit of Epidemiology, Karolinska Institutet said that the results show that the higher the apoB/apoA-1 value, the greater the risk of myocardial infarction, stroke, and need for coronary surgery. The study also showed that the risk was amplified in the presence of low protective levels of apoA-1.

Prof. Walldius and Niklas Hammar, professor emeritus at the Institute of Environmental Medicine at the Karolinska Universitet, also an author of the study, sent comments to Medical News Today. The apoB/apoA-1 ratio can detect those individuals who have seemingly normal or even low LDL that may not be detected by only LDL, non-HDL, or even apoB alone.