Dyslipidemia means the abnormal levels of cholesterol and other lipids in the blood. It is a major risk factor for Cardiovascular conditions. High levels of low-density lipoprotein cholesterol (LDL-C) have links to an increased risk of disease. International guidelinesTrusted Source commonly include LDL-C levels as a risk marker for Cardiovascular illnesses.
Risk markers that can assess Cardiovascular risk include high-density lipoprotein cholesterol (HDL-C), which protects against disease risk; and apoB, which transports LDL-C and other lipids linked to Cardiovascular disease to tissues in the body. ApoA-1 transports HDL-C. Research has shown that the ratios of both apoB and apoA-1 have links to an increased risk of heart attackTrusted Source and strokeTrusted Source.
Prof. Walldius and Niklas Hammar, professor emeritus at the Institute of Environmental Medicine at the Karolinska Universitet, also an author of the study, sent comments to Medical News Today. The apoB/apoA-1 ratio can detect those individuals who have seemingly normal or even low LDL that may not be detected by only LDL, non-HDL, or even apoB alone.